This should be a fun week for Fantasy lineups. With the six teams on a bye, as well as players dealing with injuries, you might have some interesting players starting for you this week. For example, quarterbacks like Matt Moore, Brian Hoyer and Ryan Tannehill could look attractive in favorable matchups. Running backs you might have to rely on include Kareem Hunt, J.D. McKissic and Gus Edwards – if you're lucky.

At receiver, guys like Zach Pascal, DeVante Parker and Ted Ginn could be must-start options, as well as tight ends like Mike Gesicki, Vance McDonald and Jonnu Smith. Desperate times call for desperate lineups, and you might be stuck in some deeper leagues.

It's not easy having to replace stars like Deshaun Watson, Tom Brady, Carson Wentz, Phillip Lindsay, Leonard Fournette, DeAndre Hopkins, Courtland Sutton, Julian Edelman, D.J. Chark and Zach Ertz, among others, who are on bye. And then you have key injuries to players like Adam Thielen (hamstring), T.Y. Hilton (calf), Brandin Cooks (concussion), Evan Engram (foot), James Conner (shoulder) and Patrick Mahomes (knee).

With the Fantasy playoffs approaching in a few weeks, you need wins. So whoever helps you accomplish that goal, plug them into your lineup and hope for the best.

We'll do our part to help with the best suggestions for your roster. And hopefully Week 10 is successful for you in your matchups.

Editor's Note: Projections are provided by CBS Sports and not Jamey Eisenberg. Projected points are for PPR leagues.

Start 'Em & Sit 'Em

Welcome back to the Jameis Winston roller coaster. Strap in, because you never know what twists and turns await. 

It's been a wild ride again with Winston in 2019. There have been several highs, including five games with at least 21 Fantasy points. And a few lows, including three games with 14 Fantasy points or less, highlighted with a six-turnover outing in Week 6 against Carolina in London.

He comes into Week 10 against Arizona on a nice two-game stretch with his Fantasy production with consecutive games of 23 Fantasy points. But in those two outings against Tennessee and Seattle he has five turnovers, and nothing seems to come easy for Winston.

This week, he should have the chance for a monster game. The Cardinals are No. 2 in Fantasy points allowed to opposing quarterbacks, and only Russell Wilson in Week 4 and Daniel Jones in Week 7 have failed to score at least 22 Fantasy points against this defense. Six quarterbacks have actually scored at least 32 Fantasy points against Arizona, including the past two with Drew Brees and Jimmy Garoppolo.

You also get the narrative of Buccaneers coach Bruce Arians facing his former team since he was the Cardinals coach from 2012-17. Maybe Arians wants to prove something to his former employer and allow Winston the chance for some extra production.

There's always risk with trusting Winston. But this feels like a relatively safe scenario for him to succeed, especially since he's playing at home for the first time since Week 3. I'm confident Winston will deliver a big game against the Cardinals.

I'm starting Winston over: Dak Prescott (vs. MIN), Jared Goff (at PIT), Matt Ryan (vs. NO), Matthew Stafford (at CHI), Kirk Cousins (at DAL)

Ravens (at CIN) —12.1 projected points

• Colts (vs. MIA)
• Giants (at NYJ)
• Rams (at PIT)

Panthers (at GB) – 6.6 projected points