News

German court halts site preparation for Tesla factory
2020-02-17 08:37:20
A German court has temporarily halted the site preparation for Tesla Inc.'s first electric car factory in Europe.
Faculty of Architecture Admission System
2020-02-17 07:21:48
Personal Information Collection Statement
Opinion | Chinese Hacking Is Alarming. So Are Data Brokers.
2020-02-17 06:57:07
Companies like Equifax threaten our personal privacy and our national security.
Opinion | The Equality That Wasn’t Enough
2020-02-17 06:45:23
The most radical Radical Republicans had a better idea of how to cast the 15th Amendment. We should have listened to them.
Tech Waste Is a Danger to Us All
2020-02-17 06:12:06
Industry and governments are ignoring the problem—as well as some simple solutions
Chinese Telecommunications Conglomerate Huawei and Subsidiaries Charged in Racketeering Conspiracy and Conspiracy to Steal Trade Secrets
2020-02-17 05:50:10
A superseding indictment was returned yesterday in federal court in Brooklyn, New York, charging Huawei Technologies Co. Ltd. (Huawei), the world’s largest telecommunications equipment manufacturer, and two U.S. subsidiaries with conspiracy to violate the Racketeer Influenced and Corrupt Organizations Act (RICO).
'Animals live for man': China's appetite for wildlife likely to survive virus
2020-02-17 03:29:50
HONG KONG/BEIJING (Reuters) - For the past two weeks China's police have been raiding houses, restaurants and makeshift markets across the country, arresting nearly 700 people for breaking the temporary ban on catching, selling or eating wild animals. The scale of the crackdown, which has netted
Apple news and rumors since 1997
2020-02-17 00:06:11
appleinsider.com rumors and news on everything apple since 1997
Facial expressions don't tell the whole story of emotion
2020-02-16 19:08:38
Interacting with other people is almost always a game of reading cues and volleying back. We think a smile conveys happiness, so we offer a smile in return. We think a frown shows sadness, and maybe we attempt to cheer that person up.
Insider Q&A: Facebook VP of Messenger discusses privacy
2020-02-16 19:08:37
At Facebook, Stan Chudnovsky oversees the Messenger chat app that's used by well over 1 billion people each month. He's playing a key role in helping Facebook integrate that app with its other chat tools, WhatsApp and Instagram Direct.
Why Xi's 'defensive' coronavirus speech could backfire
2020-02-16 17:39:22
Chinese state media published an internal speech delivered by President Xi Jinping on Saturday in which he describes taking action on the coronavirus outbreak as early as Jan. 7.In the speech, which was given Feb. 3, Xi said he had "issued demands about the efforts to prevent and control" the
Try This on For Size: China Decides to Invade North Korea
2020-02-16 17:36:52
Aren't they allies? It's not so simple.
67 new cases of coronavirus confirmed on cruise ship that has quarantined Americans
2020-02-16 17:31:24
Sixty-seven new cases of coronavirus were confirmed on the Diamond Princess cruise ship Saturday, as the U.S. government is set to evacuate Americans who have been quarantined since last week. A statement from Princess Cruises on the new cases said the cruise line is following guidance from Japan'
Boris Johnson curbs photographers’ access to No 10
2020-02-16 14:53:25
News organisations accuse Downing Street staff of excluding them from high-profile events
The global fight against coronavirus
2020-02-16 13:58:18
In just a couple of months the new coronavirus that emerged from the Chinese city of Wuhan has spread around the world, sparking a race to find treatments and vaccines against it.
5 Years After Indiana's Historic HIV Outbreak, Many Rural Places Remain At Risk
2020-02-16 13:25:48
Fewer than a third of the 220 counties deemed by the federal government as vulnerable to similar outbreaks have active syringe exchange programs which can stop the spread of the infection.
The Comfortable Life is Killing You
2020-02-16 13:22:21
Society tames the wolf into a dog. And man is the most domesticated animal of all.
Smartphone voting stirs interest—and security fears
2020-02-16 11:36:08
West Virginia's disabled residents and overseas military personnel will be able to vote by smartphone in the US presidential election this year, the latest development in a push to make balloting more accessible despite persistent security fears.
Cloud computing: invisible, versatile and highly profitable
2020-02-16 11:20:03
With each passing quarter, Amazon, Microsoft and Google have been setting new records, while cloud computing has become the invisible backbone supporting much of our daily lives. Its potential to become an even bigger part of people's daily existence is sky-high.
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
2020-02-16 09:48:11
Ralph Baric, Vineet Menachery and colleagues characterize a SARS-like coronavirus circulating in Chinese horseshoe bats to determine its potential to infect primary human airway epithelial cells, cause disease in mice and respond to available therapeutics. The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV underscores the threat of cross-species transmission events leading to outbreaks in humans. Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations1. Using the SARS-CoV reverse genetics system2, we generated and characterized a chimeric virus expressing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone. The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV. Additionally, in vivo experiments demonstrate replication of the chimeric virus in mouse lung with notable pathogenesis. Evaluation of available SARS-based immune-therapeutic and prophylactic modalities revealed poor efficacy; both monoclonal antibody and vaccine approaches failed to neutralize and protect from infection with CoVs using the novel spike protein. On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo. Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.

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